The purpose of this study was to expose body to oxygen deficit via interval hypoxic training to assess blood factors. In interval hypoxic training, subjects controlled their respires in specific steps. For intensity exert, exercises began from three steps and finished with six steps (Jar example, step 1, 2, 3 inspiration - step 4, 5, 6 inspire retention and step 7, 8, 9 expiration). Before and after the exercises, hemogolobin, hematocrite reticolucite and red blood cells measured. Subjects were physical education students (n = 30, age = l&e2) divided in to three groups. Expremental group performed interval running and another expremental group perfomed interval hypoxic training and the control group didn’t physical activity. The results indicated that effect of interval running on hemogolobin, reticulocite and red blood cells was not significeant but in hematocrite was. So, effect of interval hypoxic running on four factors was significant. ANOVA inicated that there is a significant different between three groups.